Chemical characteristics of the carbon-fluorine bond.-The physica properties of the carbon-fluorine bond.-Some metabolic aspects of fluorine bond.- Effects of fluoro compounds on metabolic control in brain mitochondria.-Fluorine as a substituent of oxigen in biological systems: examples in mammalian membrane transport and glycosidase actio.-The nucleotides of fluorinated pyrimidines and their biological activities.-Fluoroamino acids and protein synthesis.-Synthesis and reactivity of fluorocarbohydrates.-The metabolism and enzymology of fluorocarbohydrates and related compound.-Nuclear magnetic resonance studies of macromolecules with fluorine nuclei as probes.-Chemistry of fluorosteroids and their hormonal properties.-Biochemical effects of fluoroacetate poisoning in rat liver.-The use of microorganisms in the study of fluorinated compounds.-Clinical and pathological effects of fluoride toxicity in animals.-